PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1083
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeEscherichia coli O18A   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe O-polysaccharide part consists of the following residues : -2)α-L-Rhap(1-->6)α-D-Glcp(1-->4)α-D-Galp [branched to β-D-GlcpNAc(1-->3)] (1-->3)α-D-GlcpNAc [branched to α-D-Glcp(1-->6)] (1-
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesBoiled E. coli 018A bacteria
Carrier NameNil
Conjugation MethodNil
AntibodiesMab PL13
Antibody type and classIgM
Assay SystemELISA, immunoblotting and Bacterial agglutination tests, competitive inhibition assays
Cross-reactivityThis Mab was specific to E. coli strain 018A and 018A2 but cross-reacted with S. marcescens 08 LPS
Proposed epitopesN-acetyl-D-glucosamine seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation24-01-2010
ReferencesPMC261100


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