PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1168
Carbohydrate NameSmooth Lipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBordetella parapertusis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe O-chain of these bacteria was reported as a homopolymer of 1,4-linked 2,3-diacetamido-2,3- dideoxy-α-galacturonic acid. This polymer contains several amidated uronic acids, the number of which varies between strains
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesB. parapertusis whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab PP8
Antibody type and classIgG3
Assay SystemELISA and ELISA Inhibition assay
Cross-reactivityThis Mab did not react with the B. pertussis LPS but cross-reacted with B. bronchiseptica LPS
Proposed epitopesThe epitope was found to reside on O-chains in addition to sugar units in the core
IEDB EpitopeN/A
Proposed UtilityThis Mab was used for structurural elucidation of the epitope
Curator IDAA + AS
Date of Curation25-02-2010
References7524956


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