PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1146
Carbohydrate NameHigh molecular weight polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeBacteroides fragilis NCTC 9343   (NCBI Taxonomy)   (Drugpedia)
Basic Structure-3)α-D-FucpNAc4N(1-->4)α-D-GalpNAc [branched to β-D-Galf(1-->3)] (1-->3)β-D-Galp [branched via 6th and 4th positions to RPyr(2-(1-.C73
BCSDB StructureN/A
Proposed functionsCapsular polysaccharide of B. fragilis may represent a virulence factor
Antigenic Nature used to produce antibodiesWhole cells of a B. fragilis NCTC 9343 enriched for expression of the EDL
Carrier NameNil
Conjugation MethodNil
AntibodiesMab QUBf8
Antibody type and classIgG1
Assay SystemImmunoblotting, immunofluorescence, flow cytometry
Cross-reactivityThis Mab did not cross-react with B. vulgatus, B. thetawtaomicron, B. ovatus, B. distasonis, B. gingivalis, E. coli or S. aureus. But it reacted with B. fragilis strain BE6
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation16-02-2010
References1719202


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