PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2206
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeSerogroup D Salmonella   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part of Salmonella enterica group D LPS is as follows : -2)-α-D-Manp [branched to α-Tyvp-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp [branched to α-D-Glcp-(1-->4)]-(1-
BCSDB StructureN/A
Proposed functionsLPS plays an important virulence role based on its antiphagocytic and endotoxic properties
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab SA:5D12A
Antibody type and classN/A
Assay SystemELISA
Cross-reactivityThis Mab reacted with Salmonella serogroups A-E and a rough strain of S. cholerae-suis
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThe usefulness of Mabs can be generated for diagnostic and protective purposes
Curator IDAA + AS
Date of Curation03-03-2011
References8770643


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036