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PolysacDB ID | 1630 |
Carbohydrate Name | Antigen 5 (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Mycobacterium tuberculosis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Antigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Unheated, lyophilized M. tuberculosis H37Ra culture filtrate solids |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab TB-C-1 |
Antibody type and class | IgM |
Assay System | Affinity chromatography, ELISA |
Cross-reactivity | This Mab cross-reacted with M. kansasii |
Proposed epitopes | Arabinomannan residues seemed to be a part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 25-09-2010 |
References | PMC265954 |
PolysacDB ID | 1744 |
Carbohydrate Name | Arabinogalactan and arabinomannan (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Mycobacterium tuberculosis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Mycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues, and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | M. tuberculosis culture filtrate |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab TB-C-1 |
Antibody type and class | IgM |
Assay System | ELISA, immunoblotting, Immunosorbent affinity chromatography and Immunoelectrophoresis |
Cross-reactivity | This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare |
Proposed epitopes | N/A |
IEDB Epitope | 76830 |
Proposed Utility | This Mab would allow the purification of important mycobacterial antigens antigens |
Curator ID | AA + AS |
Date of Curation | 20-10-2010 |
References | PMC1577034 |
PolysacDB ID | 1746 |
Carbohydrate Name | Antigen 5 (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Mycobacterium tuberculosis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Antigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | M. tuberculosis culture filtrate |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab TB-C-1 |
Antibody type and class | IgM |
Assay System | ELISA, immunoabsorbent affinity chromatography |
Cross-reactivity | This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare and also cross-reacted with antigen 6 from Mycobacterium tuberculosis |
Proposed epitopes | Arabinomannan and arabinogalactan residues seemed to be a part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab would allow the purification of important mycobacterial antigens antigens |
Curator ID | AA + AS |
Date of Curation | 20-10-2010 |
References | PMC265954 |
Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |