PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1752
Carbohydrate NameAntigen 5   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeMycobacterium tuberculosis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureAntigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesM. tuberculosis culture filtrate
Carrier NameNil
Conjugation MethodNil
AntibodiesMab TB-C-7
Antibody type and classIgM
Assay SystemELISA, immunoabsorbent affinity chromatography
Cross-reactivityThis Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare and also cross-reacted with antigen 6 from Mycobacterium tuberculosis
Proposed epitopesArabinomannan and arabinogalactan residues seemed to be a part of the epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab would allow the purification of important mycobacterial antigens antigens
Curator IDAA + AS
Date of Curation22-10-2010
ReferencesPMC265954


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