| PolysacDB ID | 2437 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype Y (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap-(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1-
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| BCSDB Structure | 113249 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab Y-A2 |
| Antibody type and class | IgM |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 4a LPS |
| Proposed epitopes | Mab Y-A2 exhibits distinct preference for the oligosaccharide α-L-Rha(1-->2)α-L-Rha(1-->3)α-L-Rha(1-->3)βGlcNac |
| IEDB Epitope | 76696 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 13-05-2011
|
| References | 3531329 |