PolysacDB ID | 2445 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Shigella flexneri serotype Y (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap-(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1-
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BCSDB Structure | 113249 |
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Phenol killed cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab Y-B5 |
Antibody type and class | IgM |
Assay System | ELISA, immunodiffusion |
Cross-reactivity | This Mab was highly cross-reactive and cross-reacted with 1b, 2b, 3a, 4a and X LPS |
Proposed epitopes | This Mab reacted with alkali-treated LPS |
IEDB Epitope | 76696 |
Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
Curator ID | AA + AS |
Date of Curation | 16-05-2011
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References | 3531329 |