PolysacDB ID | 1033 |
Carbohydrate Name | Lipoarabinomannan (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Mycobacterium leprae (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Mycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor
|
BCSDB Structure | 127448 |
Proposed functions | T cell proliferation and to interfere with gamma interferon-mediated activation of macrophages |
Antigenic Nature used to produce antibodies | Whole killed mycobacteria leprae cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab lam204 |
Antibody type and class | IgM |
Assay System | Sandwich ELISA |
Cross-reactivity | This antibody cross-reacted with cross-reacted to a large number of mycobacterial species such as M. tuberculosis, M. bovis, M leprae, M. phlei and M. avium |
Proposed epitopes | N\A |
IEDB Epitope | N/A |
Proposed Utility | These antibodies could be used to detect mycobacterial antigens in sputum |
Curator ID | AA + AS |
Date of Curation | 09-01-2010
|
References | 2127645 |