PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2188
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeSerogroup C1 (0:6,7) Salmonella   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-β-D-Manp-(1-->2)-α-D-Manp [branched to α-D-Glcp-(1-->3)] -(1-->2)-α-D-Manp-(1-->2)-α-D-Manp-(1-->3)-β-D-GlcpNAc-(1-
BCSDB StructureN/A
Proposed functionsLPS plays an important virulence role based on its antiphagocytic and endotoxic properties
Antigenic Nature used to produce antibodiesO6 coated Salmonella thompson bacteria
Carrier NameNil
Conjugation MethodNil
AntibodiesMouse Mab 5
Antibody type and classIgG1
Assay SystemELISA
Cross-reactivityThis Mab was specific to the immunizing strain and did not react with other strains
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation25-02-2011
References1693643


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