PolysacDB ID | 1042 |
Carbohydrate Name | Glucan (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Neurospora crassa (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Glucans are a heterogeneous group of glucose polymers, consisting of a backbone of β(1-->3)-linked β-D-glucopyranosyl units with β(1-->6)-linked side chains of varying distribution and length
|
BCSDB Structure | N/A |
Proposed functions | Activates leukocytes, stimulating their phagocytic, cytotoxic, and antimicrobial activities, including the production of reactive oxygen and nitrogen intermediates |
Antigenic Nature used to produce antibodies | Homogenous suspension of hyphal walls. |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | S4D1 |
Antibody type and class | IgM |
Assay System | ELISA, immunofluorescence |
Cross-reactivity | This antibody was cross-reactive with A.nidulans, Schiz.commune. |
Proposed epitopes | 1,3-α-glucan |
IEDB Epitope | N/A |
Proposed Utility | Screening of fungi for presence of 1,3-α-glucan in hyphae cell wall. |
Curator ID | AA + AS |
Date of Curation | 13-01-2010
|
References | 9245814 |