| PolysacDB ID | 1041 |
| Carbohydrate Name | Phosphocholine (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Pneumococcal strain WU(12) (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Phosphocholine (PC) is an intermediate in the synthesis of phosphatidylcholine in tissues. Phosphocholine is made in a reaction, catalyzed by choline kinase, that converts ATP + Choline into Phosphocholine and ADP
|
| BCSDB Structure | N/A |
| Proposed functions | Phosphocholine is determinant of lipotechoic acids of Gram positive bacteria |
| Antigenic Nature used to produce antibodies | Cell extract and heat killed Pneumococcal strain EF3296. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | SR4W1 |
| Antibody type and class | IgG2a |
| Assay System | Blood bactericidal assay, hemolytic activity |
| Cross-reactivity | N/A |
| Proposed epitopes | Phosphocholine |
| IEDB Epitope | N/A |
| Proposed Utility | Monoclonal antibody SR4W1 can protect mice against Pneumococcal infections. |
| Curator ID | AA + AS |
| Date of Curation | 12-01-2010
|
| References | PMC313299 |