PolysacDB ID | 1004 |
Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Haemophilus influenzae type B (NCBI Taxonomy) (Drugpedia) |
Basic Structure | A relatively simple antigen consisting of repeating units of 3-β-D ribose-(1-->1)-D-ribitol-5-phosphate
|
BCSDB Structure | 23423
|
Proposed functions | An important virulence determinant |
Antigenic Nature used to produce antibodies | Glycoconjugates |
Carrier Name | Neisseria meningitidis group B outer membrane protein complex (Hib PS-OMP) |
Conjugation Method | The strategy uses a oligopeptide spacer molecule whose parts are derived from both modified Haemophilus influenzae capsular polysaccharide and Neisseria meningitides group B outer membrane complex |
Antibodies | Polysera |
Antibody type and class | IgG1 and IgG2 |
Assay System | N\A |
Cross-reactivity | N/A |
Proposed epitopes | N\A |
IEDB Epitope | N/A |
Proposed Utility | These antibodies exert their protective effect by initiating complement-mediated activities including opsonization and bacterial lysis |
Curator ID | AA + AS |
Date of Curation | 01-01-2010
|
References | PMC296547 |