PolysacDB ID | 1038 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Rhizobium leguminosarum (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is composed of three parts: (1) lipid A, (2) core polysaccharide, and (3) O antigen. The lipid A region contains two glucosamine sugar derivatives, each with three fatty acids and phosphate or pyrophosphate attached. The core polysaccharide has KDO and attached to lipid A. The side chain O is small polysaccharide chain extending outward from the core, it has several peculiar sugars and varies in composition between bacterial strains.
|
BCSDB Structure | 1686
|
Proposed functions | LPS is most unusual constituents of outer membrane. It plays important role in host defence avoidance. LPS contributes to the negative charge of the bacterial surface. Lipid A is often toxic and act as endotoxin |
Antigenic Nature used to produce antibodies | Mixture of suspension of cell envelop. |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 3 |
Antibody type and class | N\A |
Assay System | Western blotting, spot imunoassays, agglutination tests |
Cross-reactivity | This antibody was cross-reactive with different strains of R.leguminosarum like R.biovars viciae, trifolli and phaseoli. |
Proposed epitopes | N/A
|
IEDB Epitope | N/A |
Proposed Utility | N\A |
Curator ID | AA + AS |
Date of Curation | 10-01-2010
|
References | PMC209711 |