| PolysacDB ID | 1039 |
| Carbohydrate Name | Capsular polysaccharides K5 (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Escherichia coli (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Capsular polysacchirides K5 is disaccharide with repeating unit 4-β-GlcUA(1-->4)-α-GlcNAc
|
| BCSDB Structure | N/A |
| Proposed functions | Capsular polysaccharides are responsible for pathogen`s virulence |
| Antigenic Nature used to produce antibodies | Whole formalinized E.coli cells. |
| Carrier Name | N/A |
| Conjugation Method | N/A |
| Antibodies | Mab 865 |
| Antibody type and class | IgM |
| Assay System | Indirect ELISA, Immunoblot analysis |
| Cross-reactivity | This antibody was cross-reactive with ECA of E.coli and S.typhimurium strains. |
| Proposed epitopes | 4-β-GlcUA(1-->4)-α-GlcNAc |
| IEDB Epitope | N/A |
| Proposed Utility | Reaction pattern of Mab with whole cell bacteria indicate that ECA and outer core in encapsulated bacteria are not readily accessible to antibodies.This suggests that these common envelop structures may not be useful antigens for vaccine development. |
| Curator ID | AA + AS |
| Date of Curation | 11-01-2010
|
| References | PMC261975 |