PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1067
Carbohydrate NameEnterobacterial common antigen   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeEscherichia coli C600   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt is a glycophospholipid built up by an amino sugar heteropolymer linked to an L-glycerophosphatidyl residue.
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole formalinized E. coli C600 cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 865
Antibody type and classIgM
Assay SystemELISA and immunoblotting
Cross-reactivityThis antibody cross-reacted with purified ECA from S.montevideo and to E. coli Rl and R4 LPS, cross-reacted well with the K5 capsular polysaccharide
Proposed epitopesEpitope was proposed to contain 4-linked α-N-acetylglucosamine
IEDB EpitopeN/A
Proposed UtilityThis Mab may be used for the detection of ECA and K5 core structures but also for analysis of the molecular forms resolved on polyacrylamide gels (banding patterns)
Curator IDAA + AS
Date of Curation20-01-2010
ReferencesPMC261975


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036