PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1070
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis Serogroup B   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide, also known as K-antigen consists of repeating units of following residues : -8)α-Neup5Ac(2- [a homopolymer of α(2-->8) sialic acid residues]
BCSDB Structure139710
Proposed functionsN/A
Antigenic Nature used to produce antibodiesLive group B type 15 meningococci cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 2-2-B
Antibody type and classIgM
Assay SystemELISA and Radioimmunoassay
Cross-reactivityThis antibody cross-reacted with E. coli strain K1 Capsular polysaccharide
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab provided protection against the E. coli K-1 strain
Curator IDAA + AS
Date of Curation21-01-2010
ReferencesPMC261141


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