PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us
Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1514
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeKlebsiella strains KD37   (NCBI Taxonomy)   (Drugpedia)
Basic StructureO-1 side chain of the LPS is proposed to contain a disaccharide repeat unit consisting of [-α-D-Galp-(1->3)-β-D-Galf-] (1->4), where Gal is galactose
BCSDB StructureN/A
Proposed functionsThese major cell surface antigens play important roles in the ability of the bacterium to evade host cell defenses
Antigenic Nature used to produce antibodiesFormalinized whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemELISA and immunoblotting
Cross-reactivityThis antisera reacted with the full complement of High molecular weight LPS and Low molecular weight LPS but had no apparent response against the lipid A core
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis antibody may help in the stuctural and functional elucidation of O1 side chain of Klebsiella LPS
Curator IDAA + AS
Date of Curation09-08-2010
ReferencesPMC259910


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036