| PolysacDB ID | 1578 |
| Carbohydrate Name | N-propionylated group B meningococcal polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Neisseria meningitidis Serogroup B (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It is a homopolymer of α(2-->8) sialic acid
|
| BCSDB Structure | N/A |
| Proposed functions | This capsular polysaccharide is an important virulence determinant. Serum antibodies to the group B polysaccharide confers protection against disease by activating complement-mediated bacteriolysis and/or opsonization. It leads to immunologic tolerance induced by prenatal exposure to host polysialyated glycoproteins |
| Antigenic Nature used to produce antibodies | Glycoconjugates |
| Carrier Name | Tetanus toxoid |
| Conjugation Method | Nil |
| Antibodies | Polysera |
| Antibody type and class | N/A |
| Assay System | Radioactive binding inhibition assay, ELISA, Bactericidal assay |
| Cross-reactivity | This antisera cross-reacted with capsular polysaccharide of E. coli K1 |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This antisera was bactericidal for Group B meningococci |
| Curator ID | AA + AS |
| Date of Curation | 12-09-2010
|
| References | 2469720 |