PolysacDB ID | 1761 |
Carbohydrate Name | Peptide mimotope (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Mycobacterium tuberculosis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The peptide consisted of the following sequence : QEPLMGTVPIRAGGGS
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Purified peptide |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Polysera |
Antibody type and class | N/A |
Assay System | ELISA, immunoblotting |
Cross-reactivity | This antisera recognized mannosylated Mycobacterium tuberculosis cell-wall antigens arabinomannan, lipoarabinomannan and the glycosylated recombinant protein Apa. The antisera also cross-reacted with mannans from Saccharomyces cerevisiae, but did not react with phosphatidyl-inositol-di-mannoside or arabinogalactan from Mycobacteria |
Proposed epitopes | The epitope was proposed to be oligomannosidic in nature |
IEDB Epitope | N/A |
Proposed Utility | This peptide mimotope can used as surrogate reagent for immunodiagnosis of tuberculosis |
Curator ID | AA + AS |
Date of Curation | 24-10-2010
|
References | PMC1134969 |