PolysacDB ID | 1889 |
Carbohydrate Name | Capsular polysaccharide (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Neisseria meningitidis Serogroup B (NCBI Taxonomy) (Drugpedia) |
Basic Structure | It consists of a homopolymer of α(2-->8)-linked sialic acid residues
|
BCSDB Structure | 7487
|
Proposed functions | It is an important virulence factor |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MB22 |
Antibody type and class | IgM |
Assay System | Counter immunoelectrophoresis and slide agglutination tests |
Cross-reactivity | This Mab was specific to group B polysaccharide and did not cross-react with Haemophilus influenza and Streptococcus pneumoniae. This Mab also cross-reacted with N. meningitidis group C polysaccharide antigen, an alpha (2->9)-linked homopolymer of sialic acid residues |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab can be used in culture identification. |
Curator ID | AA + AS |
Date of Curation | 23-11-2010
|
References | PMC269298 |