PolysacDB ID | 1903 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Pasteurella multocida serotype 1 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS molecule is composed of three regions consisting of lipid A, core oligosaccharides, and O-antigen polysaccharides. The O-antigen part consists of the following residues : -3)-β-D-Galp-(1-->3)-β-D-GalpNAc-(1-->4)-β-D-Galp-(1-. The core oligosaccharide part consists of the following residues : β-D-Galp-(1-->7)-D-gro-α-D-manHepp-(1-->6)-D-gro-α-D-manHepp-(1-->6)-β-D-Glcp-(1-->4)-L-gro [branched to L-gro-α-D-manHepp-(1-->2)-L-gro-α-D-manHepp-(1-->3)] and [branched to α-D-Glcp-(1-->6)] -α-D-manHepp-(1--/lipid A
|
BCSDB Structure | N/A |
Proposed functions | LPS is well known for its biological activities, including modification of metabolic activity and phagocytic function, alteration of migration of neutrophils and macrophages, and mitogenesis of lymphocytes |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Antisera |
Antibody type and class | N/A |
Assay System | ELISA |
Cross-reactivity | This antisera was specific to serotype 1 cells |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This antisera may be useful in defining antigenic determinants of LPS. |
Curator ID | AA + AS |
Date of Curation | 25-11-2010
|
References | PMC271284 |