PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1906
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePasteurella multocida serotype 12   (NCBI Taxonomy)   (Drugpedia)
Basic StructureLPS molecule is composed of three regions consisting of lipid A, core oligosaccharides, and O-antigen polysaccharides
BCSDB StructureN/A
Proposed functionsLPS is well known for its biological activities, including modification of metabolic activity and phagocytic function, alteration of migration of neutrophils and macrophages, and mitogenesis of lymphocytes
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesAntisera
Antibody type and classN/A
Assay SystemELISA
Cross-reactivityThis antisera cross-reacted with serotype 4 cells
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis antisera may be useful in defining antigenic determinants of LPS.
Curator IDAA + AS
Date of Curation25-11-2010
ReferencesPMC271284


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