| PolysacDB ID | 1999 |
| Carbohydrate Name | Disaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe | Streptococcus pneumoniae serotype 6B (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The structure of the disaccharide is α-L-Rhap-(1-->4)-D-Rib-ol-[5-->P-->(CH2)3NH2]
|
| BCSDB Structure | 5205
|
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Glycoconjugates |
| Carrier Name | Keyhole limpet hemocyanin |
| Conjugation Method | The saccharides were coupled via the 3-aminopropyl spacer to carrier protein KLH in a stepwise reaction: the amino-terminal groups of the OS fragment and KLH were activated by S acetylation and Br acetylation, respectively, and coupled via a thioether linkage |
| Antibodies | Antisera |
| Antibody type and class | N/A |
| Assay System | ELISA, phagocytosis assays and protection experiments |
| Cross-reactivity | This antisera was specific to capsular polysaccharide of strain 6B and did not cross-react with 6A strains |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This antisera could passively protect mice against a 6B challenge |
| Curator ID | AA + AS |
| Date of Curation | 14-12-2010
|
| References | PMC97953 |