PolysacDB ID | 2207 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Salmonella enteritidis (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Salmonella enteritidis lipopolysaccharide is composed of high-molecular-weight (HMW) LPS and low-molecular-weight (LMW) LPS. The HMW LPS O-antigen polysaccharides are comprised of two different repeating units, -[-->2)-[α-Tyvp-(1-->3)]beta-D-Manp-(1-->4)-α-L-R hap-(1-->3)-α-D-Galp-(1-->]- (structure I) and [-->2)-[α-Tyvp-(1-->3)]β-D-Manp-(1-->4)-α--L-R hap-(1-->3)-[α-D-Glcp-(1-->4)]α-D-Galp-(1-->]- (structure II). The LMW LPS contains truncated O-antigen polysaccharide which is comprised of only structure I. |
BCSDB Structure | 128190
|
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Heat killed Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab 178H11 |
Antibody type and class | IgA |
Assay System | ELISA and immunoblotting |
Cross-reactivity | This Mab recognized O:9 antigen of subserogroup OD1 LPS as well as LPS from S. enteritidis |
Proposed epitopes | This Mab is directed to O:9 antigen of the LPS |
IEDB Epitope | N/A |
Proposed Utility | This Mab agglutinated all Salmonella OD1 strains and all S. enteritidis clinical isolates |
Curator ID | AA + AS |
Date of Curation | 04-03-2011
|
References | 11267782 |