PolysacDB ID | 2229 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Salmonella minnesota Re chemotype 595 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : α-Kdop-(2-8)-α-Kdop-(2-->4)-Kdo
|
BCSDB Structure | 147530
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Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Heat killed bacteria |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MASM3 |
Antibody type and class | IgG2b |
Assay System | Enzyme immunoassay, ELISA |
Cross-reactivity | This Mab cross-reacted with Salmoneela typhimurium SL1102 Re chemotype LPS |
Proposed epitopes | 3-deoxy-D-mannooctulosonic acid [KDO] residues at the terminal non-reducing ends seemed to be the part of the epitope |
IEDB Epitope | N/A |
Proposed Utility | This Mab would help elucidate the Kdo LPS domain structure |
Curator ID | AA + AS |
Date of Curation | 14-03-2011
|
References | 2033255 |