PolysacDB ID | 2266 |
Carbohydrate Name | Y O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Shigella flexneri (NCBI Taxonomy) (Drugpedia) |
Basic Structure | The O-LPS consists of a tetrasaccharide repeating unit α-L-Rhap-(1-->2)-α-L-Rhap(1-->3)- . This tetrasaccharide is polymerized and joined by β-1,2 linkages between N-acetyl-D-glucosamine and L-rhamnosyl to form the O-polysaccharide chain
|
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Heat-killed S. flexnerf bacteria serotype Y |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MASF Y-2 |
Antibody type and class | N/A |
Assay System | ELISA, FARR assay |
Cross-reactivity | MASF Y-2 bound exclusively to LPS of serotype Y. In the glycoconjugate ELISA. these antibodies bound only to the octa- and decasaccharide-BSA antigens |
Proposed epitopes | This Mab bound to intrachain determinants |
IEDB Epitope | 76764 |
Proposed Utility | This Mab would help in the delineation of the antigenic stucture of Y O polysaccharide |
Curator ID | AA + AS |
Date of Curation | 15-03-2011
|
References | 2438343 |