| PolysacDB ID | 2270 |
| Carbohydrate Name | Y O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The O-LPS consists of a tetrasaccharide repeating unit α-L-Rhap-(1-->2)-α-L-Rhap(1-->3)- . This tetrasaccharide is polymerized and joined by β-1,2 linkages between N-acetyl-D-glucosamine and L-rhamnosyl to form the O-polysaccharide chain
|
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Heat-killed S. flexnerf bacteria serotype Y |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Antisera |
| Antibody type and class | N/A |
| Assay System | ELISA, FARR assay |
| Cross-reactivity | The polyclonal rabbit anti-group antigen 3.4 antibodies reacted with the lb, 2a, 3b, 4a. 4b, and Y LPS. They did not bind to1a and 5a. In glycoconjugate ELISA's it bound to all saccharides especially abcd- and decasaccharide- BSA antigens |
| Proposed epitopes | Antigen 3,4 seemed to be the epitope |
| IEDB Epitope | 76696 |
| Proposed Utility | This Mab would help in the delineation of the antigenic stucture of Y O polysaccharide |
| Curator ID | AA + AS |
| Date of Curation | 16-03-2011
|
| References | 2438343 |