PolysacDB ID | 2279 |
Carbohydrate Name | O-polysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Shigella flexneri serotype 6 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | O-specific chain of Shigella flexneri 6 lipopolysaccharide was found to be composed mainly of rhamnose, N-acetylgalactosamine and O-acetyl groups. The structure of which is as follows: --[3-GlcNAc-1-->3-Rha 1-->2-Rha-1--]n,where the terminal rhamnose residue may be linked to another rhamnose residue via 1-->4 linkage. |
BCSDB Structure | 188
|
Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MASF VI-1 |
Antibody type and class | IgG3 |
Assay System | ELISA |
Cross-reactivity | This Mab was specific to serotype 6 |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab may prove to be valuable reagents in the studies of protective immunity against Shigella bacteria |
Curator ID | AA + AS |
Date of Curation | 17-03-2011
|
References | 2437036 |