PolysacDB ID | 2507 |
Carbohydrate Name | Core oligosaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Vibrio cholerae 01 serogroup (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A
|
BCSDB Structure | N/A |
Proposed functions | V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera |
Antigenic Nature used to produce antibodies | Purified LPS |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab E8 |
Antibody type and class | IgG1 |
Assay System | Enzyme-linked immunosorbent assayinhibition experiments, Coagglutination experiments |
Cross-reactivity | This Mab cross-reacted with both 0-group 1 vibrios and some non-O-group 1 vibrios |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab may provide improved opportunities for the characterization of antigenic determinants |
Curator ID | AA + AS |
Date of Curation | 09-06-2011
|
References | PMC347760 |