PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1136
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeActinobacillus pleuropneumoniae serotype 5   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues.
BCSDB Structure108568
Proposed functionsLPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
Antibodies5Mab-1
Antibody type and classIgM
Assay SystemELISA inhibition tests
Cross-reactivityThis Mab was specific to serotype 5 strains
Proposed epitopesThe epitope was proposed to consist of of β-1,6-linked D-galactose residues
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for specially distinguishing serotype 5 strains
Curator IDAA + AS
Date of Curation12-02-2010
References1384404


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036