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| PolysacDB ID | 1510 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strains 81-750 and B78-3760 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | O-polysaccharide structure of strain 81-750 is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells of strains 81-750 and B78-3760 and LPS coated whole cells of strain 81-750. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 3B4 |
| Antibody type and class | IgG1 |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with CPS of serotype 5b |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 08-08-2010 |
| References | PMC1263782 |
| PolysacDB ID | 1511 |
| Carbohydrate Name | Lipopolysaccharide and capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Actinobacillus pleuropneumoniae serotype b strains 81-750 and B78-3760 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | O-polysaccharide structure of strain 81-750 is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
| BCSDB Structure | N/A |
| Proposed functions | LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus |
| Antigenic Nature used to produce antibodies | Formaldehyde killed cells of strains 81-750 and B78-3760 and LPS coated whole cells of strain 81-750. |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab 3A5 |
| Antibody type and class | IgG1 |
| Assay System | ELISA and dot ELISA |
| Cross-reactivity | This antibody cross-reacted strongly with CPS of serotype 5b |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals |
| Curator ID | AA + AS |
| Date of Curation | 08-08-2010 |
| References | PMC1263782 |
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Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036 |