PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 3

Entry No. - 1   [TOP]
PolysacDB ID1149
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeBacteroides fragilis NCTC 9344   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsLPS polysaccharide of B. fragilis may represent a virulence factor
Antigenic Nature used to produce antibodiesLive cells of B. fragilis strains NCTC 9344
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemImmunoblotting
Cross-reactivityN/A
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation17-02-2010
References2432160


Entry No. - 2   [TOP]
PolysacDB ID1153
Carbohydrate NamePolysaccharide A   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeBacteroides fragilis NCTC 9344   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt contained predominantly galactose, N-acetylgalactosamine, and an unidentified amino sugar
BCSDB StructureN/A
Proposed functionsThis forms a part of the capsular polysaccharide of B. fragilis which is an important virulence factor
Antigenic Nature used to produce antibodiesFormalin-killed whole B. fragilis cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab CE3
Antibody type and classIgG3
Assay SystemImmunoblotting, immunofluorescence
Cross-reactivityN/A
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab may help in the elucidation of variability of surface polysaccharide structures
Curator IDAA + AS
Date of Curation19-02-2010
ReferencesPMC257968


Entry No. - 3   [TOP]
PolysacDB ID1154
Carbohydrate NamePolysaccharide B   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeBacteroides fragilis NCTC 9344   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt contained fucose (15%), galactose (23%), quinovosamine (27%), and glucosamine (23%)
BCSDB StructureN/A
Proposed functionsThis forms a part of the capsular polysaccharide of B. fragilis which is an important virulence factor
Antigenic Nature used to produce antibodiesFormalin-killed whole B. fragilis cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab F10
Antibody type and classIgG2a
Assay SystemImmunoblotting, immunofluorescence
Cross-reactivityN/A
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab may help in the elucidation of variability of surface polysaccharide structures
Curator IDAA + AS
Date of Curation19-02-2010
ReferencesPMC257968


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