PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

Total Entries - 3
Entry No. - 1 [TOP]

PolysacDB ID	1333
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Candida albicans 3153A (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Cell wall extract of wild-type Candida albicans 3153A
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab 17e4
Antibody type and class	N/A
Assay System	ELISA, Immunofluorescence and immunoblotting
Cross-reactivity	This antibody cross-reacted with strains 4B, 4C, 24, 37, 53, and 22 but did not cross-react with 4A, 16, 28, 47, and 62
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab agglutinated Candida albicans cells
Curator ID	AA + AS
Date of Curation	16-06-2010
References	PMC281022

Entry No. - 2 [TOP]

PolysacDB ID	1334
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Candida albicans 3153A (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Cell wall extract of wild-type Candida albicans 3153A
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab C6
Antibody type and class	N/A
Assay System	ELISA, Immunofluorescence and immunoblotting
Cross-reactivity	This antibody cross-reacted with strain 62, B, 4C, 24, 37, 53, and 22 but did not react with 4A, 16, 28 and 47 strains
Proposed epitopes	The epitope is supposed to contain high concentrations of glucose and mannose and is present in the acid-labile oligomannosaccharides.
IEDB Epitope	N/A
Proposed Utility	N/A
Curator ID	AA + AS
Date of Curation	18-06-2010
References	PMC281022

Entry No. - 3 [TOP]

PolysacDB ID	1335
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Candida albicans 3153A (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Cell wall extract of wild-type Candida albicans 3153A
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab B6
Antibody type and class	N/A
Assay System	ELISA, Immunofluorescence and immunoblotting
Cross-reactivity	This antibody cross-reacted with strain 62, B, 4C, 24, 37, 53, and 22 but did not react with 4A, 16, 28 and 47 strains
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	N/A
Curator ID	AA + AS
Date of Curation	18-06-2010
References	PMC281022

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036