PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1345
Carbohydrate NameMannan   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeCandida albicans NIH A-207   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesPolyclonal Antisera
Antibody type and classN/A
Assay SystemOuchterlony double immunodiffusion
Cross-reactivityThe antisera did not cross-react with C. albicans NIH B-792 but cross-reracted with Hormodendrum strains, H. pedrosoi IFO 6071, H. compactum IFO 6726, and H. dermatitidis IFO 6421
Proposed epitopesThe epitope was proposed to consist of α-D-mannopyranosyl residues occupying the nonreducing terminals of the branching moieties
IEDB Epitope76848
Proposed UtilityThis antisera was used to study the structural similarities between Candida mannans and Hormemendrum galactomannans
Curator IDAA + AS
Date of Curation24-06-2010
ReferencesPMC260140


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