PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1374
Carbohydrate NameUnknown carbohydrate   (Drugpedia)
Carbohydrate ClassGlycoprotein
MicrobeCoccidioides immitis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesCoccidiodin along with spherulin
Carrier NameNil
Conjugation MethodNil
AntibodiesMab
Antibody type and classIgG1
Assay SystemELISA, immunoblotting and 2d-immunoelectrophoresis
Cross-reactivityThis antibody was specific to Coccidiodes and did not cross-react with histoplasmin and blastocyanin
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis MAb would be useful as a probe for detecting circulating antigen in patients with coccidioidal disease and to assess the effect of passively transferred Mab on the pathogenesis of experimental murine coccidioidomycosis
Curator IDAA + AS
Date of Curation02-07-2010
ReferencesPMC313225


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