PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 3

Entry No. - 1   [TOP]
PolysacDB ID1087
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeEikenella corrodens FDC 1073   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities
BCSDB StructureN/A
Proposed functionsThe lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis
Antigenic Nature used to produce antibodiesLPS preparations from E. corrodens FDC
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ECF-1
Antibody type and classIgM
Assay SystemELISA, immunodiffusion, immunoblotting
Cross-reactivityThis antibody showed cross-reactivity with LPS from F. nucleatum ATCC 25586
Proposed epitopesThis Mab recognized a core region epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens
Curator IDAA + AS
Date of Curation25-01-2010
ReferencesPMC313151


Entry No. - 2   [TOP]
PolysacDB ID1088
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeEikenella corrodens FDC 1073   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities
BCSDB StructureN/A
Proposed functionsThe lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis
Antigenic Nature used to produce antibodiesLPS preparations from E. corrodens FDC
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ECF-2
Antibody type and classIgM
Assay SystemELISA, immunodiffusion, immunoblotting
Cross-reactivityThis antibody showed cross-reactivity with LPS from F. nucleatum ATCC 25586
Proposed epitopesThis Mab recognized a core region epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens
Curator IDAA + AS
Date of Curation25-01-2010
ReferencesPMC313151


Entry No. - 3   [TOP]
PolysacDB ID1089
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeEikenella corrodens FDC 1073   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities
BCSDB StructureN/A
Proposed functionsThe lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis
Antigenic Nature used to produce antibodiesLPS preparations from E. corrodens FDC
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ECF-3
Antibody type and classIgG3
Assay SystemELISA, immunodiffusion, immunoblotting
Cross-reactivityThis antibody cross-reacted with LPSs from C. ochracea M-12 and F. necrophorum ATCC 25286
Proposed epitopesThe epitope consists of D-galactose and L-rhamnose residues and recognizes an O-side chain epitope
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens
Curator IDAA + AS
Date of Curation26-01-2010
ReferencesPMC313151


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