PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

Total Entries - 5
Entry No. - 1 [TOP]

PolysacDB ID	1482
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Histoplasma capsulatum (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Disrupted yeast cell homogenate of Histoplasma capsulatum
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab 1
Antibody type and class	IgG2b
Assay System	ELISA, immunoblotting and Solid-phase radioimmunoassay
Cross-reactivity	This Mab cross-reacted with H. capsulatum and Blastomyces dermatitidis
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	MAbs may prove useful in the development of more specific immunodiagnostic tests for histoplasmosis
Curator ID	AA + AS
Date of Curation	30-07-2010
References	PMC313195

Entry No. - 2 [TOP]

PolysacDB ID	1483
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Histoplasma capsulatum (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Disrupted yeast cell homogenate of Histoplasma capsulatum
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab 2
Antibody type and class	IgG3
Assay System	ELISA, immunoblotting and Solid-phase radioimmunoassay
Cross-reactivity	This Mab cross-reacted with H. capsulatum and Blastomyces dermatitidis
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	MAbs may prove useful in the development of more specific immunodiagnostic tests for histoplasmosis
Curator ID	AA + AS
Date of Curation	31-07-2010
References	PMC313195

Entry No. - 3 [TOP]

PolysacDB ID	1484
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Histoplasma capsulatum (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Disrupted yeast cell homogenate of Histoplasma capsulatum
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab 3
Antibody type and class	IgG1
Assay System	ELISA, immunoblotting and Solid-phase radioimmunoassay
Cross-reactivity	MAb 3 cross-reacted with B. dermatitidis, Paracoccidioides brasiliensis, Sporothrir schenckii, and Candida albicans
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	MAbs may prove useful in the development of more specific immunodiagnostic tests for histoplasmosis
Curator ID	AA + AS
Date of Curation	31-07-2010
References	PMC313195

Entry No. - 4 [TOP]

PolysacDB ID	1485
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Histoplasma capsulatum (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Disrupted yeast cell homogenate of Histoplasma capsulatum
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab 4
Antibody type and class	IgG3
Assay System	ELISA, immunoblotting and Solid-phase radioimmunoassay
Cross-reactivity	MAb 4 cross-reacted with B. dermatitidis, C. albicans, Coccidioides immitis, Aspergillus fumigatus, and Mycobacterium tuberculosis
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	MAbs may prove useful in the development of more specific immunodiagnostic tests for histoplasmosis
Curator ID	AA + AS
Date of Curation	31-07-2010
References	PMC313195

Entry No. - 5 [TOP]

PolysacDB ID	1486
Carbohydrate Name	Unknown carbohydrate (Drugpedia)
Carbohydrate Class	Glycoprotein
Microbe	Histoplasma capsulatum (NCBI Taxonomy) (Drugpedia)
Basic Structure	N/A
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Semipurified M antigen of histoplasmin
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab CB4
Antibody type and class	IgM
Assay System	Immunoprecipitation and Enzyme Immunoassay
Cross-reactivity	This antibody cross-reacted with Blastomyces dermatitidis and Coccidioides immitis
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	N/A
Curator ID	AA + AS
Date of Curation	31-07-2010
References	PMC260824

Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036