PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1804
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis Serogroup Y   (NCBI Taxonomy)   (Drugpedia)
Basic StructureSerogroup Y capsular polysaccharides are heteropolymers, composed of α-2-6-linked sialic acid and galactose or glucose respectively.
BCSDB Structure3214
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 5-1-Y
Antibody type and classIgM
Assay SystemELISA
Cross-reactivityThis Mab was specific to Serogroup Y and did not cross-react with other serogroups even though weak reactions was seen with cells of serogroup D, 29E, H, I, K, and L meningococci
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab would help in serogrouping of Neisseria meningitidis strains
Curator IDAA + AS
Date of Curation04-11-2010
ReferencesPMC540207


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