PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 2

Entry No. - 1   [TOP]
PolysacDB ID1875
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis group A   (NCBI Taxonomy)   (Drugpedia)
Basic StructureNeisseria meningitidis serogroup A capsular polysaccharide (CPS) is composed of a homopolymer of O-acetylated, α1-->6-linked ManNAc 1-phosphate
BCSDB Structure3136
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 06B4
Antibody type and classN/A
Assay SystemELISA, dot blot assay, immunoblotting
Cross-reactivityThis Mab reacted with L11 serotype only
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation20-11-2010
ReferencesPMC259622


Entry No. - 2   [TOP]
PolysacDB ID1876
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeNeisseria meningitidis group A   (NCBI Taxonomy)   (Drugpedia)
Basic StructureNeisseria meningitidis serogroup A capsular polysaccharide (CPS) is composed of a homopolymer of O-acetylated, α1-->6-linked ManNAc 1-phosphate
BCSDB Structure3136
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab D6A
Antibody type and classN/A
Assay SystemELISA, dot blot assay, immunoblotting
Cross-reactivityThis Mab reacted with L11 serotype only
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation20-11-2010
ReferencesPMC259622


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