PolysacDB ID | 1879 |
Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
Carbohydrate Class | Lipopolysaccharide |
Microbe | Neisseria meningitidis group A strain 4402 (NCBI Taxonomy) (Drugpedia) |
Basic Structure | Neisseria meningitidis serogroup A capsular polysaccharide (CPS) is composed of a homopolymer of O-acetylated, α1-->6-linked ManNAc 1-phosphate |
BCSDB Structure | 3136 |
Proposed functions | It is an important virulence factor |
Antigenic Nature used to produce antibodies | Whole cells |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab MCA14.2 |
Antibody type and class | N/A |
Assay System | Coagglutination, enzyme-linked immunosorbent assay and immunoblotting |
Cross-reactivity | This Mab cross-reacted with a group A strain having the L10 serotype and a group B meningococcal strain and Haemophilus influenzae type B, but not with the lipopolysaccharides of several strains of Salmonella typhi, Escherichia coli, Streptococcus pneumoniae, and Neisseria gonorrhoeae |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | N/A |
Curator ID | AA + AS |
Date of Curation | 21-11-2010
|
References | PMC264378 |