PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1879
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeNeisseria meningitidis group A strain 4402   (NCBI Taxonomy)   (Drugpedia)
Basic StructureNeisseria meningitidis serogroup A capsular polysaccharide (CPS) is composed of a homopolymer of O-acetylated, α1-->6-linked ManNAc 1-phosphate
BCSDB Structure3136
Proposed functionsIt is an important virulence factor
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MCA14.2
Antibody type and classN/A
Assay SystemCoagglutination, enzyme-linked immunosorbent assay and immunoblotting
Cross-reactivityThis Mab cross-reacted with a group A strain having the L10 serotype and a group B meningococcal strain and Haemophilus influenzae type B, but not with the lipopolysaccharides of several strains of Salmonella typhi, Escherichia coli, Streptococcus pneumoniae, and Neisseria gonorrhoeae
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation21-11-2010
ReferencesPMC264378


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