PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 2

Entry No. - 1   [TOP]
PolysacDB ID2151
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa Serotype O11   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe structure of the O-polysaccharide of Pseudomonas aeruginosa O11 has been reported to be comprised of trisaccharide repeating-units as follows: -->3)-α-L-FucpNAc-(1-->1)-β-D-FucpNAc-(1--> 2)-β-D-Glcp-(1-->. (FucpNAc, 2-acetamido-2,6-dideoxygalactopyranoside.)
BCSDB Structure22424
Proposed functionsN/A
Antigenic Nature used to produce antibodiesFormalin killed whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MF55-1
Antibody type and classIgM
Assay SystemELISA, immunoblotting and Double immunodiffusion
Cross-reactivityThis Mab was specific to its homologous serotype
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator IDAA + AS
Date of Curation11-02-2011
ReferencesPMC260467


Entry No. - 2   [TOP]
PolysacDB ID2152
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa Serotype O11   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe structure of the O-polysaccharide of Pseudomonas aeruginosa O11 has been reported to be comprised of trisaccharide repeating-units as follows: -->3)-α-L-FucpNAc-(1-->1)-β-D-FucpNAc-(1--> 2)-β-D-Glcp-(1-->. (FucpNAc, 2-acetamido-2,6-dideoxygalactopyranoside.)
BCSDB Structure22424
Proposed functionsN/A
Antigenic Nature used to produce antibodiesFormalin killed whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MF50-1
Antibody type and classIgM
Assay SystemELISA, immunoblotting and Double immunodiffusion
Cross-reactivityThis Mab was specific to its homologous serotype
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator IDAA + AS
Date of Curation11-02-2011
ReferencesPMC260467


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