PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

Total Entries - 14
Entry No. - 1 [TOP]

PolysacDB ID	2089
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF5-1
Antibody type and class	IgG2b
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	16-01-2011
References	PMC260467

Entry No. - 2 [TOP]

PolysacDB ID	2090
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF5-2
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	17-01-2011
References	PMC260467

Entry No. - 3 [TOP]

PolysacDB ID	2091
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF5-3
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	17-01-2011
References	PMC260467

Entry No. - 4 [TOP]

PolysacDB ID	2092
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF5-4
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	17-01-2011
References	PMC260467

Entry No. - 5 [TOP]

PolysacDB ID	2093
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-1
Antibody type and class	N/A
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	18-01-2011
References	PMC260467

Entry No. - 6 [TOP]

PolysacDB ID	2094
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-2
Antibody type and class	N/A
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	18-01-2011
References	PMC260467

Entry No. - 7 [TOP]

PolysacDB ID	2095
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-3
Antibody type and class	N/A
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	18-01-2011
References	PMC260467

Entry No. - 8 [TOP]

PolysacDB ID	2096
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-4
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	19-01-2011
References	PMC260467

Entry No. - 9 [TOP]

PolysacDB ID	2097
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-5
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	19-01-2011
References	PMC260467

Entry No. - 10 [TOP]

PolysacDB ID	2098
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-6
Antibody type and class	N/A
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	20-01-2011
References	PMC260467

Entry No. - 11 [TOP]

PolysacDB ID	2099
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-7
Antibody type and class	N/A
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	20-01-2011
References	PMC260467

Entry No. - 12 [TOP]

PolysacDB ID	2100
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-8
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	21-01-2011
References	PMC260467

Entry No. - 13 [TOP]

PolysacDB ID	2101
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-9
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	21-01-2011
References	PMC260467

Entry No. - 14 [TOP]

PolysacDB ID	2102
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O3 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF57-10
Antibody type and class	N/A
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	21-01-2011
References	PMC260467

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