PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613

Total Entries - 9
Entry No. - 1 [TOP]

PolysacDB ID	2103
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-1
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	22-01-2011
References	PMC260467

Entry No. - 2 [TOP]

PolysacDB ID	2104
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-2
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	22-01-2011
References	PMC260467

Entry No. - 3 [TOP]

PolysacDB ID	2105
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-3
Antibody type and class	IgG2b
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	23-01-2011
References	PMC260467

Entry No. - 4 [TOP]

PolysacDB ID	2106
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-4
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	24-01-2011
References	PMC260467

Entry No. - 5 [TOP]

PolysacDB ID	2107
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-5
Antibody type and class	IgG2b
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	24-01-2011
References	PMC260467

Entry No. - 6 [TOP]

PolysacDB ID	2108
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-6
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	24-01-2011
References	PMC260467

Entry No. - 7 [TOP]

PolysacDB ID	2109
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-7
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	24-01-2011
References	PMC260467

Entry No. - 8 [TOP]

PolysacDB ID	2110
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-8
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	25-01-2011
References	PMC260467

Entry No. - 9 [TOP]

PolysacDB ID	2111
Carbohydrate Name	O-polysaccharide (Drugpedia)
Carbohydrate Class	Lipopolysaccharide
Microbe	Pseudomonas aeruginosa Serotype O4 (NCBI Taxonomy) (Drugpedia)
Basic Structure	The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB Structure	N/A
Proposed functions	N/A
Antigenic Nature used to produce antibodies	Formalin killed whole cells
Carrier Name	Nil
Conjugation Method	Nil
Antibodies	Mab MF31-9
Antibody type and class	IgM
Assay System	ELISA, immunoblotting and Double immunodiffusion
Cross-reactivity	This Mab was specific to its homologous serotype
Proposed epitopes	N/A
IEDB Epitope	N/A
Proposed Utility	This Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator ID	AA + AS
Date of Curation	25-01-2011
References	PMC260467

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