PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us
Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 2

Entry No. - 1   [TOP]
PolysacDB ID2128
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa Serotype O7   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesFormalin killed whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MF29-1
Antibody type and classIgM
Assay SystemELISA, immunoblotting and Double immunodiffusion
Cross-reactivityThis Mab cross-reacted with serotype O8
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator IDAA + AS
Date of Curation04-02-2011
ReferencesPMC260467


Entry No. - 2   [TOP]
PolysacDB ID2129
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa Serotype O7   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-antigens consist of a trisaccharide repeating unit which consists of two uronic acid derivatives and one N-acetyl fucosamine residue
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesFormalin killed whole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab MF29-2
Antibody type and classIgM
Assay SystemELISA, immunoblotting and Double immunodiffusion
Cross-reactivityThis Mab cross-reacted with serotype O9
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used for serotyping of Pseudomonas aeruginosa strains
Curator IDAA + AS
Date of Curation04-02-2011
ReferencesPMC260467


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036