PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 18

Entry No. - 1   [TOP]
PolysacDB ID2003
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-1
Antibody type and classIgG3
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation15-12-2010
References3081727


Entry No. - 2   [TOP]
PolysacDB ID2004
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-2
Antibody type and classIgG2b
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation15-12-2010
References3081727


Entry No. - 3   [TOP]
PolysacDB ID2005
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-3
Antibody type and classIgG1
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation15-12-2010
References3081727


Entry No. - 4   [TOP]
PolysacDB ID2006
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-5
Antibody type and classIgG1
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 5   [TOP]
PolysacDB ID2007
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-6
Antibody type and classIgG1
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 6   [TOP]
PolysacDB ID2008
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-7
Antibody type and classIgM
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 7   [TOP]
PolysacDB ID2009
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-8
Antibody type and classIgM
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 8   [TOP]
PolysacDB ID2010
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-9
Antibody type and classIgG3
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 9   [TOP]
PolysacDB ID2011
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-10
Antibody type and classIgG3
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 10   [TOP]
PolysacDB ID2012
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-11
Antibody type and classIgG3
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 11   [TOP]
PolysacDB ID2013
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-12
Antibody type and classIgM
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation16-12-2010
References3081727


Entry No. - 12   [TOP]
PolysacDB ID2014
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-13
Antibody type and classIgM
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation17-12-2010
References3081727


Entry No. - 13   [TOP]
PolysacDB ID2015
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-14
Antibody type and classIgG3
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation17-12-2010
References3081727


Entry No. - 14   [TOP]
PolysacDB ID2016
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-15
Antibody type and classIgM
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation18-12-2010
References3081727


Entry No. - 15   [TOP]
PolysacDB ID2017
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-16
Antibody type and classIgM
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation18-12-2010
References3081727


Entry No. - 16   [TOP]
PolysacDB ID2018
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab ES-P-1S-17
Antibody type and classIgG3
Assay SystemELISA, passive protection tests
Cross-reactivityThis Mab was specific to PVA-1 antigen
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab had invivo protective activity
Curator IDAA + AS
Date of Curation18-12-2010
References3081727


Entry No. - 17   [TOP]
PolysacDB ID2019
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodies antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 1.5
Antibody type and classN/A
Assay SystemN/A
Cross-reactivityThis Mab was specific to serotype 1 LPS
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation19-12-2010
References9364


Entry No. - 18   [TOP]
PolysacDB ID2020
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa serotype 1   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
BCSDB Structure9364
Proposed functionsN/A
Antigenic Nature used to produce antibodiesSerotype 1 component from polyvalent pseudomonas vaccine [PPV]
Carrier NameNil
Conjugation MethodNil
AntibodiesMab 1.7
Antibody type and classN/A
Assay SystemN/A
Cross-reactivityThis Mab was specific to serotype 1 LPS
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation19-12-2010
References9364


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