PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2071
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas aeruginosa strain Fisher IT-3   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core oligosaccharide of P. aeruginosa can be divided into outer and inner core regions. The inner core consists of 2-keto-3-deoxyoctonate (Kdo), heptose, and large amounts of phosphate and is believed to be homogeneous among serotypes. The outer core of P. aeruginosa contains D-glucose (D-Glc), L-rhamnose (L-Rha), D-galactosamine (D-GalN), and L-alanine (L-Ala]
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesAlkali treated LPS
Carrier NameNil
Conjugation MethodNil
AntibodiesAntisera
Antibody type and classN/A
Assay SystemELISA, opsonophagocytic assays, animal protection studies and immunoblotting
Cross-reactivityThis antisera was highly cross-reactive
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis antisera had opsonophagocytic activity against LPS rough strains
Curator IDAA + AS
Date of Curation07-01-2011
ReferencesPMC172952


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