PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2062
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas syringae IMV P-55 pv. Morsprunorum   (NCBI Taxonomy)   (Drugpedia)
Basic StructureO-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab Ps2d
Antibody type and classIgG3
Assay SystemAgglutination, Ouchterlony immunodiffusion, ELISA, SDS-PAGE, and Western immunoblotting
Cross-reactivityMAb Ps2d reacted with some strains with pathovar morsprunorum and also reacted with GSPB 839 as well as all strains with pathovar lapsa
Proposed epitopesThe epitope of Mab 2d is related to the lateral immunodominant (α1-4)D-fucose residues
IEDB EpitopeN/A
Proposed UtilityThis Mab strongly agglutinated homologous bacterial cells and precipitated soluble antigens
Curator IDAA + AS
Date of Curation03-01-2011
ReferencesPMC178531


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036