PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2063
Carbohydrate NameO-polysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobePseudomonas syringae serogroup O1 strain helianthi CFBP 2149   (NCBI Taxonomy)   (Drugpedia)
Basic StructureO-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesMab Ps(1-2)a1
Antibody type and classIgG1
Assay SystemELISA, agglutination and immunoblotting
Cross-reactivity"This Mab cross-reacts with chemotypes 1B, 1C-1A, 2A, and 2D-2A but not with those of chemotypes 1C, 1D, 1D-1A, and 2D"
Proposed epitopesMAb Ps(1-->2)α1 is specific to a region of the linkage between the OPS and the LPS core, which is suggested to be the same in all P. syringae O1 and O2 LPSs
IEDB EpitopeN/A
Proposed UtilityThis Mab agglutinated heat-killed homologous bacterial cells
Curator IDAA + AS
Date of Curation04-01-2011
ReferencesPMC94168


Bioinformatics Centre, Institute of Microbial Technology, Sec - 39A, Chandigarh, India - 160036