| PolysacDB ID | 2174 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Salmonella paratyphi A (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-α-D-Manp [branched to α-Parp-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp [branched to α-D-Glcp-(1-->4)] -(1-
|
| BCSDB Structure | 108599
|
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Formalin fixed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MO2 |
| Antibody type and class | IgG1 |
| Assay System | ELISA, immunoblotting |
| Cross-reactivity | This Mab was specific to lipopolysaccharide of Salmonella paratyphi A, and did not react against lipopolysaccharides of other Salmonella serogroups, including those of serogroups B, C, D, E, and L |
| Proposed epitopes | Dideoxyhexose residues are believed to be the immunodominant epitope for Mab M02 |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab can facilitate the routine identification of salmonella and detailed studies of their lipopolysaccharides |
| Curator ID | AA + AS |
| Date of Curation | 22-02-2011
|
| References | PMC269428 |